Ontology highlight
ABSTRACT:
SUBMITTER: Ehrlund A
PROVIDER: S-EPMC5663208 | biostudies-literature | 2017 Oct
REPOSITORIES: biostudies-literature
Ehrlund Anna A Acosta Juan R JR Björk Christel C Hedén Per P Douagi Iyadh I Arner Peter P Laurencikiene Jurga J
Scientific data 20171031
Obesity affects gene expression and metabolism of white adipose tissue (WAT), which results in insulin resistance (IR) and type 2 diabetes. However, WAT is a heterogeneous organ containing many cell types that might respond differently to obesity-induced changes. We performed flow cytometry sorting and RNA expression profiling by microarray of major WAT cell types (adipocytes, CD45-/CD31-/CD34+ progenitors, CD45+/CD14+ monocytes/ macrophages, CD45+/CD14- leukocytes), which allowed us to identify ...[more]