Ontology highlight
ABSTRACT:
SUBMITTER: Ren C
PROVIDER: S-EPMC5671735 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Ren Chengda C Shi Hui H Jiang Juanjuan J Liu Qingyu Q Du Yaru Y He Mengmei M Cai Wenting W Wei Qingquan Q Yu Jing J
Journal of ophthalmology 20171022
The aims of this study were to evaluate the effects of CM082 on the development of choroidal neovascularization (CNV) in a laser-induced CNV rat model and to determine the drug concentration in the ocular tissues. After the laser-induced CNV model was established in rats, CM082 was orally administered. The effects of CM082 on the CNV lesions were assessed using fundus fluorescein angiography (FFA), CNV histology, and retinal pigment epithelium- (RPE-) choroid-sclera eyecup analysis. The concentr ...[more]