Identification of a gene signature associated with radiotherapy and prognosis in gliomas.
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ABSTRACT:
SUBMITTER: Li S
PROVIDER: S-EPMC5687662 | biostudies-literature | 2017 Oct
REPOSITORIES: biostudies-literature
Publications
Identification of a gene signature associated with radiotherapy and prognosis in gliomas.
Li Shu S Shi Juanhong J Gao Hongliang H Yuan Yan Y Chen Qi Q Zhao Zhenyu Z Wang Xiaoqiang X Li Bin B Ming LinZhao L Zhong Jun J Zhou Ping P He Hua H Tao Bangbao B Li Shiting S
Oncotarget 20171006 51
Glioma is one of the most common primary brain tumors with poor prognosis. Although radiotherapy is an important treatment method for gliomas, the efficacy is still limited by the high occurrence of radioresistance and the underlying molecular mechanism is unclear. Here, we performed a data mining work based on four glioma expression datasets. These datasets were classified into training set and validation set. Radiotherapy-induced differential expressed genes and prognosis-associated genes were ...[more]
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