Ontology highlight
ABSTRACT:
SUBMITTER: Schaefer K
PROVIDER: S-EPMC5697233 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Schaefer Kellie K Mahajan MaryAnn M Gore Anuradha A Tsang Stephen H SH Bassuk Alexander G AG Mahajan Vinit B VB
BMC research notes 20171121 1
<h4>Objective</h4>Our objective was to characterize CAPN5 gene expression in the mouse central nervous system. Mouse brain and eye sections were probed with two high-affinity RNA oligonucleotide analogs designed to bind CAPN5 RNA and one scramble, control oligonucleotide. Images were captured in brightfield.<h4>Results</h4>CAPN5 RNA probes were validated on mouse breast cancer tumor tissue. In the eye, CAPN5 was expressed in the ganglion cell, inner nuclear and outer nuclear layers of the retina ...[more]