The clinical significance of CXCL5 in non-small cell lung cancer.
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ABSTRACT:
SUBMITTER: Wu K
PROVIDER: S-EPMC5702175 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Publications
The clinical significance of CXCL5 in non-small cell lung cancer.
Wu Kongju K Yu Shengnan S Liu Qian Q Bai Xianguang X Zheng Xinhua X Wu Kongming K
OncoTargets and therapy 20171121
As a CXC-type chemokine, ENA78/CXCL5 is an important attractant for granulocytes by binding to its receptor CXCR2. Recent studies proved that CXCL5/CXCR2 axis plays an oncogenic role in many human cancers. However, the exact clinical significance of CXCL5 in lung cancer has not been well defined. Here, we found that the serum protein expression of CXCL5 was significantly increased in non-small cell lung cancer (NSCLC) compared with that in healthy volunteers. Immunohistochemistry staining reveal ...[more]
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