Ontology highlight
ABSTRACT:
SUBMITTER: Li GT
PROVIDER: S-EPMC5707468 | biostudies-literature | 2015 Jul
REPOSITORIES: biostudies-literature
Chemical science 20150430 7
A series of chiral triazolium salts have been synthesized from methyl l-phenylalaninate hydrochloride. The NHCs derived from this class of novel triazolium salts were found to be highly efficient catalysts in the annulation reaction of enals and 2-naphthols. These reactions proceeded with high chemoselectivity and wide substrate scope affording enantioenriched β-arylsplitomicins in good yields with up to 96% ee. ...[more]