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3D printing of bacteria into functional complex materials.

ABSTRACT: Despite recent advances to control the spatial composition and dynamic functionalities of bacteria embedded in materials, bacterial localization into complex three-dimensional (3D) geometries remains a major challenge. We demonstrate a 3D printing approach to create bacteria-derived functional materials by combining the natural diverse metabolism of bacteria with the shape design freedom of additive manufacturing. To achieve this, we embedded bacteria in a biocompatible and functionalized 3D printing ink and printed two types of "living materials" capable of degrading pollutants and of producing medically relevant bacterial cellulose. With this versatile bacteria-printing platform, complex materials displaying spatially specific compositions, geometry, and properties not accessed by standard technologies can be assembled from bottom up for new biotechnological and biomedical applications.

SUBMITTER: Schaffner M

PROVIDER: S-EPMC5711516 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature

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3D printing of bacteria into functional complex materials.

Schaffner Manuel M Rühs Patrick A PA Rühs Patrick A PA Coulter Fergal F Kilcher Samuel S Studart André R AR

Science advances 20171201 12

Despite recent advances to control the spatial composition and dynamic functionalities of bacteria embedded in materials, bacterial localization into complex three-dimensional (3D) geometries remains a major challenge. We demonstrate a 3D printing approach to create bacteria-derived functional materials by combining the natural diverse metabolism of bacteria with the shape design freedom of additive manufacturing. To achieve this, we embedded bacteria in a biocompatible and functionalized 3D pri ...[more]

PMID: 29214219

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