Non-small-cell lung cancers: a heterogeneous set of diseases.
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ABSTRACT:
SUBMITTER: Chen Z
PROVIDER: S-EPMC5712844 | biostudies-literature | 2014 Aug
REPOSITORIES: biostudies-literature
Publications
Non-small-cell lung cancers: a heterogeneous set of diseases.
Chen Zhao Z Fillmore Christine M CM Hammerman Peter S PS Kim Carla F CF Wong Kwok-Kin KK
Nature reviews. Cancer 20140801 8
Non-small-cell lung cancers (NSCLCs), the most common lung cancers, are known to have diverse pathological features. During the past decade, in-depth analyses of lung cancer genomes and signalling pathways have further defined NSCLCs as a group of distinct diseases with genetic and cellular heterogeneity. Consequently, an impressive list of potential therapeutic targets was unveiled, drastically altering the clinical evaluation and treatment of patients. Many targeted therapies have been develop ...[more]
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