Dataset Information

Ergostane-Type Sterols from King Trumpet Mushroom (Pleurotus eryngii) and Their Inhibitory Effects on Aromatase.

ABSTRACT: Two new ergostane-type sterols; (22E)-5?,6?-epoxyergosta-8,14,22-triene-3?,7?-diol (1) and 5?,6?-epoxyergost-8(14)-ene-3?,7?-diol (2) were isolated from the fruiting bodies of king trumpet mushroom (Pleurotus eryngii), along with eight known compounds (3-10). All isolated compounds were evaluated for their inhibitory effects on aromatase. Among them, 4 and 6 exhibited comparable aromatase inhibitory activities to aminoglutethimide.

SUBMITTER: Kikuchi T

PROVIDER: S-EPMC5713445 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature

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Ergostane-Type Sterols from King Trumpet Mushroom (Pleurotus eryngii) and Their Inhibitory Effects on Aromatase.

Kikuchi Takashi T Motoyashiki Naoki N Yamada Takeshi T Shibatani Kanae K Ninomiya Kiyofumi K Morikawa Toshio T Tanaka Reiko R

International journal of molecular sciences 20171121 11

Two new ergostane-type sterols; (22E)-5α,6α-epoxyergosta-8,14,22-triene-3β,7β-diol (1) and 5α,6α-epoxyergost-8(14)-ene-3β,7α-diol (2) were isolated from the fruiting bodies of king trumpet mushroom (Pleurotus eryngii), along with eight known compounds (3-10). All isolated compounds were evaluated for their inhibitory effects on aromatase. Among them, 4 and 6 exhibited comparable aromatase inhibitory activities to aminoglutethimide. ...[more]

PMID: 29160820

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Dataset Information

Ergostane-Type Sterols from King Trumpet Mushroom (Pleurotus eryngii) and Their Inhibitory Effects on Aromatase.

Publications

Ergostane-Type Sterols from King Trumpet Mushroom (Pleurotus eryngii) and Their Inhibitory Effects on Aromatase.

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