Ontology highlight
ABSTRACT:
SUBMITTER: Kim BS
PROVIDER: S-EPMC5716359 | biostudies-literature | 2017 Oct
REPOSITORIES: biostudies-literature
Cell reports 20171001 1
Th17 cells are potent mediators in autoimmune diseases, and RORγt is required for their development. Recent studies have shown that RORγt<sup>+</sup> Treg cells in the gut regulate intestinal inflammation by inhibiting effector T cell function. In the current study, we report that RORγt<sup>+</sup> Treg cells were also found in lymph nodes following immunization. Not only distinct from intestinal RORγt<sup>+</sup> Treg cells in their transcriptomes, peripheral RORγt<sup>+</sup> Treg cells were d ...[more]