Epigenetic reprogramming in liver fibrosis and cancer.
Ontology highlight
ABSTRACT:
SUBMITTER: Wilson CL
PROVIDER: S-EPMC5716427 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Publications
Epigenetic reprogramming in liver fibrosis and cancer.
Wilson Caroline L CL Mann Derek A DA Borthwick Lee A LA
Advanced drug delivery reviews 20171025
Novel insights into the epigenetic control of chronic liver diseases are now emerging. Recent advances in our understanding of the critical roles of DNA methylation, histone modifications and ncRNA may now be exploited to improve management of fibrosis/cirrhosis and cancer. Furthermore, improved technologies for the detection of epigenetic markers from patients' blood and tissues will vastly improve diagnosis, treatment options and prognostic tracking. The aim of this review is to present recent ...[more]
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