Ontology highlight
ABSTRACT:
SUBMITTER: El-Miligy MM
PROVIDER: S-EPMC5729604 | biostudies-literature | 2018 Jan
REPOSITORIES: biostudies-literature
Future science OA 20171025 1
<h4>Aim</h4>Simultaneous inhibition of hepatitis C virus (HCV) and hepatocellular carcinoma (HCC) may enhance anti-HCV effects and reduce resistance and side effects.<h4>Results/methodology</h4>Novel hybrid derivatives were designed and synthesized to exhibit dual activity against HCV and its associated major complication, HCC. The synthesized compounds were screened for their potential activity against HCV and HCC. Compounds <b>5f, 5j, 5l, 5p, 5q, 5r, 6c</b> and <b>6d</b> exhibited potential <i ...[more]