Unknown

Dataset Information

0

Putative Integrative Mobile Elements That Exploit the Xer Recombination Machinery Carrying blaIMI-Type Carbapenemase Genes in Enterobacter cloacae Complex Isolates in Singapore.


ABSTRACT: Whole-genome sequencing was performed on 16 isolates of the carbapenemase-producing Enterobacter cloacae complex to determine the flanking regions of blaIMI-type genes. Phylogenetic analysis of multilocus sequence typing (MLST) targets separated the isolates into 4 clusters. The blaIMI-type genes were all found on Xer-dependent integrative mobile elements (IMEX). The IMEX elements of 5 isolates were similar to those described in Canada, while the remainder were novel. Five isolates had IMEX elements lacking a resolvase and recombinase.

SUBMITTER: Koh TH 

PROVIDER: S-EPMC5740307 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature

altmetric image

Publications

Putative Integrative Mobile Elements That Exploit the Xer Recombination Machinery Carrying <i>bla</i><sub>IMI</sub>-Type Carbapenemase Genes in Enterobacter cloacae Complex Isolates in Singapore.

Koh Tse H TH   Rahman Nurdyana Binte Abdul NBA   Teo Jeanette W P JWP   La My-Van MV   Periaswamy Balamurugan B   Chen Swaine L SL  

Antimicrobial agents and chemotherapy 20171221 1


Whole-genome sequencing was performed on 16 isolates of the carbapenemase-producing <i>Enterobacter cloacae</i> complex to determine the flanking regions of <i>bla</i><sub>IMI</sub>-type genes. Phylogenetic analysis of multilocus sequence typing (MLST) targets separated the isolates into 4 clusters. The <i>bla</i><sub>IMI</sub>-type genes were all found on Xer-dependent integrative mobile elements (IMEX). The IMEX elements of 5 isolates were similar to those described in Canada, while the remain  ...[more]

Similar Datasets

| S-EPMC4658791 | biostudies-literature
| S-EPMC10100371 | biostudies-literature
| S-EPMC4576029 | biostudies-literature
| S-EPMC6783431 | biostudies-literature
| S-EPMC6629617 | biostudies-literature
| S-EPMC9769605 | biostudies-literature
| S-EPMC10269617 | biostudies-literature
| S-EPMC9119121 | biostudies-literature
| S-EPMC163477 | biostudies-other
| S-EPMC7161257 | biostudies-literature