Ontology highlight
ABSTRACT:
SUBMITTER: Sader HS
PROVIDER: S-EPMC5740368 | biostudies-literature | 2018 Jan
REPOSITORIES: biostudies-literature
Antimicrobial agents and chemotherapy 20171221 1
A total of 10,451 contemporary (2016) <i>Enterobacteriaceae</i> isolates from 84 U.S. medical centers and 116 metallo-β-lactamase- and/or OXA-48-like-producing <i>Enterobacteriaceae</i> isolates from other countries were tested against aztreonam-avibactam and comparators. All U.S. isolates were inhibited at aztreonam-avibactam MICs of ≤8 μg/ml (MIC<sub>50</sub>, ≤0.03 μg/ml; MIC<sub>90</sub>, 0.12 μg/ml), including <i>Klebsiella pneumoniae</i> carbapenemase-producing isolates (<i>n</i> = 102; MI ...[more]