Ontology highlight
ABSTRACT:
SUBMITTER: Hill L
PROVIDER: S-EPMC5753923 | biostudies-literature | 2018 Jan
REPOSITORIES: biostudies-literature
Hill LaQuisa L Alousi Amin A Kebriaei Partow P Mehta Rohtesh R Rezvani Katayoun K Shpall Elizabeth E
Therapeutic advances in hematology 20171128 1
Graft <i>versus</i> host disease (GVHD) remains a major cause of morbidity and mortality following allogeneic hematopoietic stem-cell transplantation (HSCT). Despite the use of prophylactic GVHD regimens, a significant proportion of transplant recipients will develop acute or chronic GVHD following HSCT. Corticosteroids are standard first-line therapy, but are only effective in roughly half of all cases with ~50% of patients going on to develop steroid-refractory disease, which increases the ris ...[more]