Ontology highlight
ABSTRACT:
SUBMITTER: Wasson JA
PROVIDER: S-EPMC5765370 | biostudies-literature | 2018 Jan
REPOSITORIES: biostudies-literature
G3 (Bethesda, Md.) 20180104 1
Genomically imprinted loci are expressed mono-allelically, dependent upon the parent of origin. Their regulation not only illuminates how chromatin regulates gene expression but also how chromatin can be reprogrammed every generation. Because of their distinct parent-of-origin regulation, analysis of imprinted loci can be difficult. Single nucleotide polymorphisms (SNPs) are required to accurately assess these elements allele specifically. However, publicly available SNP databases lack robust ve ...[more]