Ontology highlight
ABSTRACT:
SUBMITTER: Dahal L
PROVIDER: S-EPMC5770965 | biostudies-literature | 2017 Dec
REPOSITORIES: biostudies-literature
Dahal Liza L Kwan Tristan O C TOC Shammas Sarah L SL Clarke Jane J
Biophysical journal 20171201 12
Understanding the detailed mechanism of interaction of intrinsically disordered proteins with their partners is crucial to comprehend their functions in signaling and transcription. Through its interaction with KIX, the disordered pKID region of CREB protein is central in the transcription of cAMP responsive genes, including those involved in long-term memory. Numerous simulation studies have investigated these interactions. Combined with experimental results, these can provide valuable and comp ...[more]