Ontology highlight
ABSTRACT:
SUBMITTER: Zhang Y
PROVIDER: S-EPMC5772166 | biostudies-literature | 2016 Aug
REPOSITORIES: biostudies-literature
Zhang Yu Y An Lin L Yue Feng F Hardison Ross C RC
Nucleic acids research 20160419 14
Advanced sequencing technologies have generated a plethora of data for many chromatin marks in multiple tissues and cell types, yet there is lack of a generalized tool for optimal utility of those data. A major challenge is to quantitatively model the epigenetic dynamics across both the genome and many cell types for understanding their impacts on differential gene regulation and disease. We introduce IDEAS, an integrative and discriminative epigenome annotation system, for jointly characterizin ...[more]