Ontology highlight
ABSTRACT:
SUBMITTER: Duncan KM
PROVIDER: S-EPMC5777297 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Duncan Kaylia M KM Mukherjee Kusumika K Cornell Robert A RA Liao Eric C EC
Developmental dynamics : an official publication of the American Association of Anatomists 20170925 11
Zebrafish is a model organism that affords experimental advantages toward investigating the normal function of genes associated with congenital birth defects. Here we summarize zebrafish studies of genes implicated in orofacial cleft (OFC). The most common use of zebrafish in this context has been to explore the normal function an OFC-associated gene product in craniofacial morphogenesis by inhibiting expression of its zebrafish ortholog. The most frequently deployed method has been to inject em ...[more]