Ontology highlight
ABSTRACT:
SUBMITTER: Liu CP
PROVIDER: S-EPMC5789950 | biostudies-literature | 2018 Jan
REPOSITORIES: biostudies-literature
Liu Chiu-Ping CP Tsai Tsung-I TI Cheng Ting T Shivatare Vidya S VS Wu Chung-Yi CY Wu Chung-Yi CY Wong Chi-Huey CH
Proceedings of the National Academy of Sciences of the United States of America 20180108 4
Monoclonal antibodies (mAbs) have been developed as therapeutics, especially for the treatment of cancer, inflammation, and infectious diseases. Because the glycosylation of mAbs in the Fc region influences their interaction with effector cells that kill antibody-targeted cells, and the current method of antibody production is relatively expensive, efforts have been directed toward the development of alternative expressing systems capable of large-scale production of mAbs with desirable glycofor ...[more]