Ontology highlight
ABSTRACT:
SUBMITTER: Kang J
PROVIDER: S-EPMC5797492 | biostudies-literature | 2018 Feb
REPOSITORIES: biostudies-literature
Kang Jianming J Ferrell Aaron J AJ Chen Wei W Wang Difei D Xian Ming M
Organic letters 20180118 3
The reactions of three model compounds (1-3) for cyclic acyl disulfides and cyclic acyl selenylsulfides are studied. These compounds were found to be effective precursors for persulfides (RSSH) and selenylsulfides (RSeSH) upon reacting with nucleophilic species. They could also act as H<sub>2</sub>S donors when interacting with cellular thiols. The most interesting discovery was the generation of RSeSH from compound 3 under mild conditions. Selenylsulfides (RSeSH) are expected to be important re ...[more]