Ontology highlight
ABSTRACT:
SUBMITTER: Heine W
PROVIDER: S-EPMC5811047 | biostudies-literature | 2018 Feb
REPOSITORIES: biostudies-literature
Heine Wiebke W Beckstette Michael M Heroven Ann Kathrin AK Thiemann Sophie S Heise Ulrike U Nuss Aaron Mischa AM Pisano Fabio F Strowig Till T Dersch Petra P
PLoS pathogens 20180201 2
Gastrointestinal infections caused by enteric yersiniae can become persistent and complicated by relapsing enteritis and severe autoimmune disorders. To establish a persistent infection, the bacteria have to cope with hostile surroundings when they transmigrate through the intestinal epithelium and colonize underlying gut-associated lymphatic tissues. How the bacteria gain a foothold in the face of host immune responses is poorly understood. Here, we show that the CNFY toxin, which enhances tran ...[more]