Ontology highlight
ABSTRACT:
SUBMITTER: Chuentragool P
PROVIDER: S-EPMC5821538 | biostudies-literature | 2018 Feb
REPOSITORIES: biostudies-literature
Journal of the American Chemical Society 20180207 7
A novel method for desaturation of aliphatic amines into enamines as well as allylic and homoallylic amines has been developed. This general protocol operates via putative aryl hybrid Pd-radical intermediates, which combine the signature features of radical chemistry, a hydrogen atom transfer (HAT) process, and transition metal chemistry, a selective β-hydride elimination step, to achieve efficient and selective desaturation of amines. These hybrid Pd-radical intermediates are efficiently genera ...[more]