Ontology highlight
ABSTRACT:
SUBMITTER: Huang Y
PROVIDER: S-EPMC5827656 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Huang Yubin Y Xu Zhen Z Xiong Shanshan S Qin Guangrong G Sun Fangfang F Yang Jian J Yuan Ti-Fei TF Zhao Lei L Wang Ke K Liang Yu-Xiang YX Fu Lin L Wu Tianzhun T So Kwok-Fai KF Rao Yanxia Y Peng Bo B
Cell discovery 20180227
Elucidating the origin of microglia is crucial for understanding their functions and homeostasis. Previous study has indicated that Nestin-positive progenitor cells differentiate into microglia and replenish the brain after depleting most brain microglia. Microglia have also shown the capacity to repopulate the retina after eliminating all retinal microglia. However, the origin(s) of repopulated retinal microglia is/are unknown. In this study, we aim to investigate the origins of repopulated mic ...[more]