Ontology highlight
ABSTRACT:
SUBMITTER: He R
PROVIDER: S-EPMC5831317 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
He Ruijun R Wang Baichuan B Cui Min M Xiong Zekang Z Lin Hui H Zhao Lei L Li Zhiliang Z Wang Zhe Z Peggrem Shaun S Xia Zhidao Z Shao Zengwu Z
Stem cells international 20180130
<h4>Background</h4>Link protein N-terminal peptide (LPP) in extracellular matrix (ECM) of cartilage could induce synthesis of proteoglycans and collagen type II in cartilaginous cells. Cartilage stem/progenitor cells (CSPCs), the endogenous stem cells in cartilage, are important in cartilage degeneration and regeneration. We hypothesized that LPP could be a stimulator for stem cell-based cartilage regeneration by affecting biological behaviors of CSPC.<h4>Methods</h4>CSPCs were isolated from rat ...[more]