Ontology highlight
ABSTRACT:
SUBMITTER: Bellono NW
PROVIDER: S-EPMC5839326 | biostudies-literature | 2017 Jun
REPOSITORIES: biostudies-literature
Bellono Nicholas W NW Bayrer James R JR Leitch Duncan B DB Castro Joel J Zhang Chuchu C O'Donnell Tracey A TA Brierley Stuart M SM Ingraham Holly A HA Julius David D
Cell 20170622 1
Dietary, microbial, and inflammatory factors modulate the gut-brain axis and influence physiological processes ranging from metabolism to cognition. The gut epithelium is a principal site for detecting such agents, but precisely how it communicates with neural elements is poorly understood. Serotonergic enterochromaffin (EC) cells are proposed to fulfill this role by acting as chemosensors, but understanding how these rare and unique cell types transduce chemosensory information to the nervous s ...[more]