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3D hyperpolarized C-13 EPI with calibrationless parallel imaging.

ABSTRACT: With the translation of metabolic MRI with hyperpolarized 13C agents into the clinic, imaging approaches will require large volumetric FOVs to support clinical applications. Parallel imaging techniques will be crucial to increasing volumetric scan coverage while minimizing RF requirements and temporal resolution. Calibrationless parallel imaging approaches are well-suited for this application because they eliminate the need to acquire coil profile maps or auto-calibration data. In this work, we explored the utility of a calibrationless parallel imaging method (SAKE) and corresponding sampling strategies to accelerate and undersample hyperpolarized 13C data using 3D blipped EPI acquisitions and multichannel receive coils, and demonstrated its application in a human study of [1-13C]pyruvate metabolism.

SUBMITTER: Gordon JW

PROVIDER: S-EPMC5856653 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature

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3D hyperpolarized C-13 EPI with calibrationless parallel imaging.

Gordon Jeremy W JW Hansen Rie B RB Shin Peter J PJ Feng Yesu Y Vigneron Daniel B DB Larson Peder E Z PEZ

Journal of magnetic resonance (San Diego, Calif. : 1997) 20180213

With the translation of metabolic MRI with hyperpolarized 13C agents into the clinic, imaging approaches will require large volumetric FOVs to support clinical applications. Parallel imaging techniques will be crucial to increasing volumetric scan coverage while minimizing RF requirements and temporal resolution. Calibrationless parallel imaging approaches are well-suited for this application because they eliminate the need to acquire coil profile maps or auto-calibration data. In thi ...[more]

PMID: 29476930

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