Ontology highlight
ABSTRACT:
SUBMITTER: Xu D
PROVIDER: S-EPMC5862632 | biostudies-literature | 2018 Mar
REPOSITORIES: biostudies-literature
Oncotarget 20180112 17
In recent years, the chimeric antigen receptor modified T cells (Chimeric antigen receptor T cells, CAR-T) immunotherapy has developed rapidly, which has been considered the most promising therapy. Efforts to enhance the efficacy of CAR-based anti-tumor therapy have been made, such as the improvement of structures of CAR-T cells, including the development of extracellular antigen recognition receptors, intracellular co-stimulatory molecules and the combination application of CARs and synthetic s ...[more]