Ontology highlight
ABSTRACT:
SUBMITTER: Pratyusha VA
PROVIDER: S-EPMC5869725 | biostudies-literature | 2018 Mar
REPOSITORIES: biostudies-literature
Scientific reports 20180327 1
Ras signaling in response to environmental cues is critical for cellular morphogenesis in eukaryotes. This signaling is tightly regulated and its activation involves multiple players. Sometimes Ras signaling may be hyperactivated. In C. albicans, a human pathogenic fungus, we demonstrate that dynamics of hyperactivated Ras1 (Ras1G13V or Ras1 in Hsp90 deficient strains) can be reliably differentiated from that of normal Ras1 at (near) single molecule level using fluorescence correlation spectrosc ...[more]