Ontology highlight
ABSTRACT:
SUBMITTER: Moore AK
PROVIDER: S-EPMC5875716 | biostudies-literature | 2018 Mar
REPOSITORIES: biostudies-literature
Neuron 20180301 6
Excitation is balanced by inhibition to cortical neurons across a wide range of conditions. To understand how this relationship is maintained, we broadly suppressed the activity of parvalbumin-expressing (PV<sup>+</sup>) inhibitory neurons and asked how this affected the balance of excitation and inhibition throughout auditory cortex. Activating archaerhodopsin in PV<sup>+</sup> neurons effectively suppressed them in layer 4. However, the resulting increase in excitation outweighed Arch suppress ...[more]