Ontology highlight
ABSTRACT:
SUBMITTER: Moyo D
PROVIDER: S-EPMC5880939 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Frontiers in immunology 20180327
Cellular activation <i>in trans</i> by interferons, cytokines, and chemokines is a commonly recognized mechanism to amplify immune effector function and limit pathogen spread. However, an optimal host response also requires that collateral damage associated with inflammation is limited. This may be particularly so in the case of granulomatous inflammation, where an excessive number and/or excessively florid granulomas can have significant pathological consequences. Here, we have combined transcr ...[more]