Ontology highlight
ABSTRACT:
SUBMITTER: Lilyquist J
PROVIDER: S-EPMC5884707 | biostudies-literature | 2018 Apr
REPOSITORIES: biostudies-literature
Lilyquist Jenna J Ruddy Kathryn J KJ Vachon Celine M CM Couch Fergus J FJ
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20180130 4
Breast cancer is the most common cancer among women in the United States, with up to 30% of those diagnosed displaying a family history of breast cancer. To date, 18% of the familial risk of breast cancer can be explained by SNPs. This review summarizes the discovery of risk-associated SNPs using candidate gene and genome-wide association studies (GWAS), including discovery and replication in large collaborative efforts such as The Collaborative Oncologic Gene-environment Study and OncoArray. We ...[more]