The IDA3 adapter, required for intraflagellar transport of I1 dynein, is regulated by ciliary length.
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ABSTRACT:
SUBMITTER: Hunter EL
PROVIDER: S-EPMC5896928 | biostudies-literature | 2018 Apr
REPOSITORIES: biostudies-literature
Publications
The IDA3 adapter, required for intraflagellar transport of I1 dynein, is regulated by ciliary length.
Hunter Emily L EL Lechtreck Karl K Fu Gang G Hwang Juyeon J Lin Huawen H Gokhale Avanti A Alford Lea M LM Lewis Brian B Yamamoto Ryosuke R Kamiya Ritsu R Yang Fan F Nicastro Daniela D Dutcher Susan K SK Wirschell Maureen M Sale Winfield S WS
Molecular biology of the cell 20180329 8
We determined how the ciliary motor I1 dynein is transported. A specialized adapter, IDA3, facilitates I1 dynein attachment to the ciliary transporter called intraflagellar transport (IFT). Loading of IDA3 and I1 dynein on IFT is regulated by ciliary length. ...[more]
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