Ontology highlight
ABSTRACT:
SUBMITTER: Khurana RK
PROVIDER: S-EPMC5937873 | biostudies-literature | 2018 Jun
REPOSITORIES: biostudies-literature
Khurana Rajneet Kaur RK Gaspar Balan Louis BL Welsby Gail G Katare O P OP Singh Kamalinder K KK Singh Bhupinder B
Drug delivery and translational research 20180601 3
The current research work encompasses the development, characterization, and evaluation of self-assembled phospholipidic nano-mixed miceller system (SPNMS) of a poorly soluble BCS Class IV xanthone bioactive, mangiferin (Mgf) functionalized with co-delivery of vitamin E TPGS. Systematic optimization using I-optimal design yielded self-assembled phospholipidic nano-micelles with a particle size of < 60 nm and > 80% of drug release in 15 min. The cytotoxicity and cellular uptake studies performed ...[more]