Ontology highlight
ABSTRACT:
SUBMITTER: Wang TY
PROVIDER: S-EPMC5940500 | biostudies-literature | 2018 May - Jun
REPOSITORIES: biostudies-literature
Wang Tony Y TY Lee Dongwon D Fox-Talbot Karen K Arking Dan E DE Chakravarti Aravinda A Halushka Marc K MK
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology 20180324
Skeletal myocytes have well-established fast and slow twitch fibers with unique gene and protein specific expression patterns. By immunohistochemical staining, these show a mosaic pattern across myocytes. We hypothesized cardiac myocytes may behave similarly where some proteins are differentially expressed between mature cardiomyocytes. We utilized the tool HPASubC on over 52,000 cardiac images of the Human Protein Atlas to identify differential protein expression patterns by immunohistochemistr ...[more]