Ontology highlight
ABSTRACT:
SUBMITTER: Gelbrich T
PROVIDER: S-EPMC5946971 | biostudies-literature | 2018 Apr
REPOSITORIES: biostudies-literature
Acta crystallographica. Section E, Crystallographic communications 20180309 Pt 4
In the salt (5α,6α)-6-[(2,5,8,11,14,17,20-hepta-oxadocosan-22-yl)-oxy]-3,14-dihy-droxy-17-(prop-2-en-1-yl)-4,5-ep-oxy-morphinan-17-ium hydrogen oxalate, C<sub>34</sub>H<sub>54</sub>NO<sub>11</sub><sup>+</sup>·C<sub>2</sub>HO<sub>4</sub><sup>-</sup> the polyether unit of the naloxegol cation adopts the shape of a squashed open letter 'O'. In the crystal, the hydrogen oxalate anions are linked into a chain by O-H⋯O hydrogen bonds. Each naloxegol unit is hydrogen bonded to three hydrogen oxalate io ...[more]