Ontology highlight
ABSTRACT:
SUBMITTER: Shen Z
PROVIDER: S-EPMC5947518 | biostudies-literature | 2015 Dec
REPOSITORIES: biostudies-literature
Chemical science 20150827 12
By designing a novel chiral ion-pair organocatalyst composed of chiral phosphate and DABCO-derived quaternary ammonium, highly enantioselective 3-<i>exo</i> iodo-cycloetherification of allyl alcohols was achieved using NIS as a halogen source. Based on this reaction, one-pot asymmetric 3-<i>exo</i> iodo-cycloetherification/Wagner-Meerwein rearrangement of allyl alcohols en route to enantioenriched 2-iodomethyl-2-aryl cycloalkanones was subsequently developed. Due to the participation of adjacent ...[more]