Dataset Information

Continuous succinic acid fermentation by Actinobacillus succinogenes in a packed-bed biofilm reactor.

ABSTRACT:

Background

Succinic acid is one of the most interesting platform chemicals that can be produced in a biorefinery approach. In this study, continuous succinic acid production by Actinobacillus succinogenes fermentation in a packed-bed biofilm reactor (PBBR) was investigated.

Results

The effects of the operating conditions tested, dilution rate (D), and medium composition (mixture of glucose, xylose, and arabinose-that simulate the composition of a lignocellulosic hydrolysate)-on the PBBR performances were investigated. The maximum succinic acid productivity of 35.0 g L^-1 h^-1 and the maximum SA concentration were achieved at a D?=?1.9 h^-1. The effect of HMF and furfural on succinic acid production was also investigated. HMF resulted to reduce succinic acid production by 22.6%, while furfural caused a reduction of 16% in SA production at the same dilution rate.

Conclusion

Succinic acid production by A. succinogenes fermentation in a packed-bed reactor (PBBR) was successfully carried out for more than 5 months. The optimal results were obtained at the dilution rate 0.5 h^-1: 43.0 g L^-1 of succinic acid were produced, glucose conversion was 88%; and the volumetric productivity was 22 g L^-1 h^-1.

SUBMITTER: Ferone M

PROVIDER: S-EPMC5950251 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature

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Publications

Continuous succinic acid fermentation by <i>Actinobacillus succinogenes</i> in a packed-bed biofilm reactor.

Ferone Mariateresa M Raganati Francesca F Ercole Alessia A Olivieri Giuseppe G Salatino Piero P Marzocchella Antonio A

Biotechnology for biofuels 20180514

<h4>Background</h4>Succinic acid is one of the most interesting platform chemicals that can be produced in a biorefinery approach. In this study, continuous succinic acid production by <i>Actinobacillus succinogenes</i> fermentation in a packed-bed biofilm reactor (PBBR) was investigated.<h4>Results</h4>The effects of the operating conditions tested, dilution rate (D), and medium composition (mixture of glucose, xylose, and arabinose-that simulate the composition of a lignocellulosic hydrolysate ...[more]

PMID: 29785205

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