Ontology highlight
ABSTRACT:
SUBMITTER: Yang L
PROVIDER: S-EPMC5980154 | biostudies-literature | 2018 Jun
REPOSITORIES: biostudies-literature
Yang Lan L Wang Xiliang X Xu Juan J Wen Ya Y Zhang Manqiao M Lu Jingxiao J Wang Rongfu R Sun Xiaojuan X
Journal of cellular and molecular medicine 20180325 6
Hepatocellular carcinoma is the most frequent primary liver cancer worldwide. The use of antioxidants as cancer prevention and treatment agents has become a focus of research in recent years due to their limited adverse effects. Alpha lipoic acid (ɑ-LA) is synthesized in the liver and is considered a naturally occurring antioxidant. In this study, a total of 4446 differentially expressed genes (2097 down-regulated and 2349 up-regulated) were identified via RNA-Seq in HepG2 cells after exposure t ...[more]