Ontology highlight
ABSTRACT:
SUBMITTER: Chung JK
PROVIDER: S-EPMC5984903 | biostudies-literature | 2018 Jan
REPOSITORIES: biostudies-literature
Chung Jean K JK Lee Young Kwang YK Denson John-Paul JP Gillette William K WK Alvarez Steven S Stephen Andrew G AG Groves Jay T JT
Biophysical journal 20180101 1
Ras is a membrane-anchored signaling protein that serves as a hub for many signaling pathways and also plays a prominent role in cancer. The intrinsic behavior of Ras on the membrane has captivated the biophysics community in recent years, especially the possibility that it may form dimers. In this article, we describe results from a comprehensive series of experiments using fluorescence correlation spectroscopy and single-molecule tracking to probe the possible dimerization of natively expresse ...[more]