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GLUT1 and lactose synthetase are critical genes for lactose synthesis in lactating sows.


ABSTRACT: Background:Lactose synthesis rate is an important factor in milk production and quality in mammals. Understanding the lactose synthesis mechanism is crucial for the improvement of milk quantity and quality. However, research on the temporal gene changes regarding lactose synthesis during the whole lactation is still limited. The objective of this study was to determine gene expression profiles related to lactose synthesis in sows during lactation, and further identify the critical steps or key factors in the lactose synthesis pathway. Methods:To determine the temporal change of factors related to lactose synthesis in sows, milk from eight multiparous Yorkshire sows (parity 3 to 6) was collected at 0 h, 2 h, 6 h, 12 h, 24 h, day 2, 3, 4, 7, 14, and 21 after birth of the first piglet. Lactose content, prolactin and progesterone concentration, and gene or protein expression related to lactose synthesis were measured. Results:The lactose yield increased gradually from D2 to D21 and reached a maximum at D14 (3-fold from D2) during lactation (P?

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC6001073 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature

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GLUT1 and lactose synthetase are critical genes for lactose synthesis in lactating sows.

Zhang Yinzhi Y   Zhang Shihai S   Guan Wutai W   Chen Fang F   Cheng Lin L   Lv Yantao Y   Chen Jun J  

Nutrition & metabolism 20180613


<h4>Background</h4>Lactose synthesis rate is an important factor in milk production and quality in mammals. Understanding the lactose synthesis mechanism is crucial for the improvement of milk quantity and quality. However, research on the temporal gene changes regarding lactose synthesis during the whole lactation is still limited. The objective of this study was to determine gene expression profiles related to lactose synthesis in sows during lactation, and further identify the critical steps  ...[more]

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