Higher expression of A-kinase anchoring-protein 1 predicts poor prognosis in human hepatocellular carcinoma.
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ABSTRACT:
SUBMITTER: Yu J
PROVIDER: S-EPMC6006472 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature
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Higher expression of A-kinase anchoring-protein 1 predicts poor prognosis in human hepatocellular carcinoma.
Yu Jian J Zhang Yu Y Zhou Dongxun D Wu Jun J Luo Rong R
Oncology letters 20180510 1
A-kinase anchoring protein 1 (AKAP1) plays important regulatory roles in the regulation of mitochondrial function, oxidative metabolism, and cell survival. However, the expression pattern and prognostic value of AKAP1 in hepatocellular carcinoma (HCC) remains unclear. AKAP1 expression levels in tumor and matched non-tumor tissues were evaluated using reverse transcription-quantitative polymerase chain reaction and immunohistochemical staining. Kaplan-Meier and Cox regression analyses were used t ...[more]
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