Ontology highlight
ABSTRACT:
SUBMITTER: Ebeling D
PROVIDER: S-EPMC6010418 | biostudies-literature | 2018 Jun
REPOSITORIES: biostudies-literature
Nature communications 20180620 1
Deciphering absolute configuration of a single molecule by direct visual inspection is the next step in compound identification, with far-reaching implications for medicinal chemistry, pharmacology, and natural product synthesis. We demonstrate the feasibility of this approach utilizing low temperature atomic force microscopy (AFM) with a CO-functionalized tip to determine the absolute configuration and orientation of a single, adsorbed [123]tetramantane molecule, the smallest chiral diamondoid. ...[more]