Architecture of PRC2 Holo Complexes.
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ABSTRACT:
SUBMITTER: Vann KR
PROVIDER: S-EPMC6014913 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature
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Architecture of PRC2 Holo Complexes.
Vann Kendra R KR Kutateladze Tatiana G TG
Trends in biochemical sciences 20180503 7
Polycomb repressive complex 2 (PRC2) is a chief epigenetic regulator. In a new article, Chen et al. describe the crystal structure of the heterotetrameric PRC2 holo complex, which provides important mechanistic insights into the organization of its subunits and the association of PRC2 with chromatin. ...[more]
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