Ontology highlight
ABSTRACT:
SUBMITTER: Bacsa I
PROVIDER: S-EPMC6017578 | biostudies-literature | 2018 Apr
REPOSITORIES: biostudies-literature
Bacsa Ildikó I Konc Csilla C Orosz Anna Boglárka AB Kecskeméti Gábor G Rigó Réka R Özvegy-Laczka Csilla C Mernyák Erzsébet E
Molecules (Basel, Switzerland) 20180403 4
Novel BODIPY-estrone conjugates were synthesized via Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC). Estrone-alkynes or an estrone-azide as starting compounds were synthesized <i>via</i> Michael addition or Sonogashira reaction as key steps. Fluorescent dyes based on BODIPY-core were provided by azide or alkyne functional groups. Fluorescent labeling of estrone was efficiently achieved at the C-2 or C-15 position. The newly-elaborated coupling procedures might have a broad applicability in t ...[more]