Ontology highlight
ABSTRACT:
SUBMITTER: Kuwabara MF
PROVIDER: S-EPMC6028957 | biostudies-literature | 2018 Jun
REPOSITORIES: biostudies-literature
The Journal of biological chemistry 20180518 26
Pendrin and prestin belong to the solute carrier 26 (SLC26) family of anion transporters. Prestin is unique among the SLC26 family members in that it displays voltage-driven motor activity (electromotility) and concurrent gating currents that manifest as nonlinear cell membrane electrical capacitance (nonlinear capacitance (NLC)). Although the anion transport mechanism of the SLC26 proteins has begun to be elucidated, the molecular mechanism of electromotility, which is thought to have evolved f ...[more]