Crystal structure of human anterior gradient protein 3.
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ABSTRACT:
SUBMITTER: Nguyen VD
PROVIDER: S-EPMC6038452 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature
Publications
Crystal structure of human anterior gradient protein 3.
Nguyen Van Dat VD Biterova Ekaterina E Salin Mikko M Wierenga Rik K RK Ruddock Lloyd W LW
Acta crystallographica. Section F, Structural biology communications 20180626 Pt 7
Oxidative protein folding in the endoplasmic reticulum is catalyzed by the protein disulfide isomerase family of proteins. Of the 20 recognized human family members, the structures of eight have been deposited in the PDB along with domains from six more. Three members of this family, ERp18, anterior gradient protein 2 (AGR2) and anterior gradient protein 3 (AGR3), are single-domain proteins which share sequence similarity. While ERp18 has a canonical active-site motif and is involved in native d ...[more]
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