Ontology highlight
ABSTRACT:
SUBMITTER: Martineau FS
PROVIDER: S-EPMC6041803 | biostudies-literature | 2018 Aug
REPOSITORIES: biostudies-literature
Martineau Fanny Sandrine FS Sahu Surajit S Plantier Vanessa V Buhler Emmanuelle E Schaller Fabienne F Fournier Lauriane L Chazal Geneviève G Kawasaki Hiroshi H Represa Alfonso A Watrin Françoise F Manent Jean-Bernard JB
Cerebral cortex (New York, N.Y. : 1991) 20180801 8
The neocortex is a 6-layered laminated structure with a precise anatomical and functional organization ensuring proper function. Laminar positioning of cortical neurons, as determined by termination of neuronal migration, is a key determinant of their ability to assemble into functional circuits. However, the exact contribution of laminar placement to dendrite morphogenesis and synapse formation remains unclear. Here we manipulated the laminar position of cortical neurons by knocking down double ...[more]