Ontology highlight
ABSTRACT:
SUBMITTER: Constanthin PE
PROVIDER: S-EPMC7561482 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Constanthin Paul E PE Contestabile Alessandro A Petrenko Volodymyr V Quairiaux Charles C Salmon Patrick P Hüppi Petra S PS Kiss Jozsef Z JZ
Development (Cambridge, England) 20201007 19
Erythropoietin (EPO), the hypoxia-inducible hematopoietic hormone, has well-established neuroprotective/neurotrophic roles in the developing central nervous system and the therapeutic potential of EPO has been widely explored in clinical studies for the treatment of perinatal hypoxic brain lesion, as well as prematurity. Here, we reveal that both EPO and Epo receptor (EPOR) are expressed in the developing rat somatosensory cortex during radial migration and laminar positioning of granular and su ...[more]