Ontology highlight
ABSTRACT:
SUBMITTER: Paiva AE
PROVIDER: S-EPMC6044472 | biostudies-literature | 2018 Jun
REPOSITORIES: biostudies-literature
Cancer research 20180522 11
The premetastatic niche formed by primary tumor-derived molecules contributes to fixation of cancer metastasis. The design of efficient therapies is limited by the current lack of knowledge about the details of cellular and molecular mechanisms involved in the premetastatic niche formation. Recently, the role of pericytes in the premetastatic niche formation and lung metastatic tropism was explored by using state-of-the-art techniques, including <i>in vivo</i> lineage-tracing and mice with peric ...[more]